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KMID : 0362119990210010139
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Journal of Technologic Dentistry
1999 Volume.21 No. 1 p.139 ~ p.144
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Nutritional and Cultural Characterizations of microorganism capable of producing antagonistic activity against Streptococcus mutans
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Park Myung-Ho
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Abstract
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The optimum culture conditions for an antibiotics from Actinomyces sp. were investigated. The optimum composition of medium for antibiotics production was 1% glucose, 1% soybean meal, 0.5% NaCl, 0.1% , and the optimum initial pH was 7.0. And the antibiotics showed highest activity when the strain isolated from soil was aerobically cultivated at for 72hours under the optimum conditions. A production of the antibiotics from Actinomyces sp. begins at the 36th hours and then reached the maximum at the stationary phase developed at the 72th hours under the optimum conditions.
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